James M. Peacock, Tetsuya Ohira, Wendy Post, Nona Sotoodehnia, Wayne Rosamond, and Aaron R. Folsom
This study suggests that low levels of serum Mg may be an important predictor of SCD, and warrants further research into the effectiveness of Mg supplementation for those considered to be at high risk for SCD.
Maes M, Leunis JC.
There is now evidence that an increased translocation of LPS from gram negative bacteria with subsequent gut-derived inflammation, i.e. induction of systemic inflammation and oxidative & nitrosative stress (IO&NS), is a new pathway in chronic fatigue syndrome (CFS).
Helmholtz Association of German Research Centres
Summary: Cortisol is responsible for the recycling of bile acids from the blood, according to new research. If this recycling is disrupted, the animals develop gallstones and lose weight because they are no longer able to digest dietary fats. They also use more energy for heat production. The researchers assume that regulation of recycling serves the purpose of conserving energy efficiently in times of need.
Tori Hudson, N.D.
Tender or lumpy breasts are one of the most common reasons why women consult their gynecologists for assessment and treatment. Since painful breasts are not always lumpy, and lumpy breasts are not always painful (and neither is usually abnormal), it is useful to create descriptive categories of symptoms and conditions to replace the generic term “fibrocystic”.
Virtually all knowledgeable health care providers agree that the term fibrocystic breast “disease” or “condition” should be abandoned in favor of a more accurate physiologically based description. First of all, the benign breast conditions that are present in almost all of us to some degree should never have been given the “disease” label in the first place. Moreover, the widespread misconception that women with painful or lumpy breasts are at increased risk of breast cancer borders on the tragic. Unfortunately, our health care system requires a diagnostic code to reimburse services, and fibrocystic breast disease has one, even though the medical literature is replete with reasons why it shouldn’t. This reinforces misinformation and fear and obscures the safe and simple means that exist for obtaining relief and reassurance.
Functional medicine is a disruptive technology that will overthrow the tyranny of the diagnosis.
– Jeffrey Bland
In assessing a patient today a new roadmap is available, one based on networks of function and causality, on a new architecture of thinking and evaluation. It is a diagnostic medicine focused on patterns and disruptions in molecular pathways leading to disturbed function. The declaration of a clinical disease is only a waypoint on the continuum of illness.
How then can we help patients view their symptoms through new lenses? What questions must we ask? How can we deduce proximal causes from diverse symptoms and measurements of physiology and biochemistry? How can we systematically reduce impediments to health and restore optimal function and the capacity for self-regulation and healing?
Chandler Marrs, PhD
From the research on AFLP, we know that a mutation in the mitochondrial enzyme responsible for processing an important mitochondrial transporter evokes some, but not all of the cases of this disease process. Notably, in some women with hyperemesis, the fetus carries the mutation and evokes the vomiting, while mom is simply a heterozygous carrier. The mutation (L-3-hydroxyacyl-CoA dehydrogenase deficiency – LCHAD) involves an enzyme (carnitine palmitoyltransferase I – CPT I) responsible for synthesizing the protein that acts as key transporter for fatty acids across the mitochondrial membrane. The protein involved is called carnitine.
While most people have heard that the mercury based preservative thimerosal was used in infant vaccines and continues to be used in several vaccine preparations, most consumers have no idea that mercury is also a commonly used ingredient in other pharmaceutical products including nasal sprays, eye drops, ear drops and injectable testosterone. Several hundred peer-reviewed scientific studies have been published over the last seven decades by leading research scientists and public health agencies confirming that thimerosal is a potent neurotoxin. It has never been proven safe for medical use—and cost-effective alternatives exist.
In the beginning, God covered the earth with broccoli and cauliflower and spinach, green and yellow and red vegetables of all kinds, so Man and Woman would live long and healthy lives. Then using God's bountiful gifts, Satan created ice cream and doughnuts. And Satan said, "You want hot fudge with that?" and Man said "Yes!" and Woman said, "I'll have another with sprinkles." And lo, they gained 10 pounds.
Hello men! I thought this would be a good time to remind you that anything you can do, I can do bleeding. That’s right, whatever it is you did today, I can probably do it while hemorrhaging from the most sensitive part of my body. And I won’t die! Remember that when you’re standing on the train in the morning surrounded by bodies — roughly half of them female bodies. They could be bleeding. Standing and bleeding. Walking and bleeding. Smiling and bleeding.
Brain iron, along with dopamine, "causes oxidative stress, inflammation, and neurodegeneration," Dr Franthal explained. "Past studies have proved there is a significantly higher iron deposition in substantia nigra in Parkinson's compared to healthy controls." So for the current study, "our objective was to investigate longitudinal changes in nigral iron concentration in PD compared with other tremor syndromes."